This is a course on
advanced concepts on protein structure and function relationships. It
presents several biophysical approaches to problems in protein-protein
and protein-ligand interactions, protein folding and structure
prediction, protein dynamics and boltzmann distributions in protein
ensembles, and principles in molecular evolution. Students are also
exposed to the most current research on the unfolded state of proteins
and hierarchical approaches to protein folding.
This substantively math based course, designed
by Dr. Panasik, draws its inspiration (and some materials with
permission) from such courses as Dr Tom Record's renowned Biophysical
Chemistry (University of Wisconsin-Madison), Drs. Song Tan & Marty
Bollinger's Proteins & Enzymes (Pennsylvania State University), and
Dr. Patrick Fleming's course in Ensembles in Protein Dynamics (Johns
Hopkins University).
The course includes multiple biophysical
chemistry problem sets, Monte Carlo atomic simulations of
protein folding and dynamics, and lab modules making use of Claflin's
3D projection system to examine the atomic structure of proteins and
protein-ligand interactions.
Course includes:
Peer Teachings (for select concepts within the
course, 5 total) - 20 points each
Assignments/Problem Sets (each week, 10 total) -75 points each
Peer Review Scoring (for each assignments, 10 total) – 25 points
each
Quizzes (on concepts from previous lecture, 10 total) – 5 points
Group Collaborations (some in class, some out of class, 5 total) –
10 points each
Exams (3 exams) – 150 points each
Peer Review Scoring (for each exam, 3 total) – 50 points each
Class Project (2 per student) – 25 points each
Class projects include taping and editing a class lecture
More to follow.
Office Hours &
Consultation
MW 10:00 a.m. – 11:30 a.m. & 1:30 p.m. – 3:00
p.m.; R 1:30 p.m. – 3:30 p.m.
We can always set an appointment for another
time via email and I am also happy to answer questions via email or
through the Blackboard Discussion board.
You can drop by at other times but I may be
busy. Feel free to send a text message to my phone to see when I am
free, or to Instant Message with me using Yahoo Messenger with screen
name: protein_structure_lab
