New approaches to inhibiting the production of cancerous cells by targeting Thymidylate Synthase
Research area is focused on the structural and functional analysis of mutant enzymes (Thymidylate Synthase). Studies include kinetic analysis, drug inhibition (resistance), antibody analysis, purification and growth complementation. Enzyme characterization utilizes UV-Vis, HPLC, FPLC and FTIR.
Detection Methods and Remediation Response to Chemical WMD
For the past three years Claflin University researchers (Bagasra, Peters, Raja) have been studying the chemistry of chemical warfare agents to develop safer methods to deactivate them. In the Peters and Raja lab we are synthesizing organic and inorganic fluorescent molecules, to be used as sensors, probes and markers.
The overall goal is to develop chemical sensors for a diverse range of chemical weapons. In the Peters lab we are studying the binding interaction of these organometallic compounds to quinolone antibiotics.